Endocrine Abstracts

Silent and post-partum thyroiditis are autoimmune conditions, which result in a triphasic thyroid hormone disturbance. They are distinguished by the later condition’s relation to pregnancy. Their association in the same patient resulting in recurrent episodes of silent thyroiditis suggests a common aetiology.We report a 32-year-old female with post-partum and recurrent silent thyroiditis continuing over a decade. She presented post-partum with thyro...

We describe below a 16-year-old male referred with neonatal hypothyroidism. He was commenced on levothyroxine at the age of 3 weeks. The TSH was >100 IU/l (normal: 0.27–4.7) and Total T4 was <10 nmol/l (normal: 60–150) and there was no uptake on thyroid isotope scanning. He was diagnosed as having congenital absence of thyroid tissue and given levothyroxine and the dose adjusted to maintain normal thyroid function. His mother was diagnosed with hypothyroidism...

Introduction: Glioblastoma, an aggressive intracranial tumour usually is a solitary lesion and not commonly located in the sella turcica. Panhypopituitarism due to multicentric glioblastoma can present with a challenging clinical picture masking or delaying the underlying diagnosis. Case presentation: 58 year old female presented with marked behavioural change, reduced appetite, nausea, polyuria & increased thirst over 4-6 weeks precipitating into an...